To mark the wedding celebrations of Emperor Leopold and Margarita Teresa of Spain in Vienna in 1666, Antonio Cesti composed the opera  »Il pomo d'oro«, which was staged in a spectacular and lavish manner unrivalled at the time. The ensemble Il Pomo d'Oro feel inspired by the cultural splendour of that time and have been performing dynamic, authentic interpretations of operas and instrumental works since 2012.

The musicians are well known specialists and are among the top in their field in the area of historically informed performance. The ensemble have worked with conductors Riccardo Minasi, Stefano Montanari, George Petrou, Enrico Onofri and Francesco Corti. Concertmaster Zefira Valova also leads the orchestra in concerts and recordings. Maxim Emelyanychev became the orchestra's chief conductor in 2016.

The ensemble is particularly known and sought-after for working with singers, whether it be solo recitals or entire opera performances and recordings.

In 2022, Il Pomo d’Oro toured with countertenor Jakub Józef Orliński with Joyce DiDonato's programme »Eden«. The ensemble's discography includes several opera recordings: Handel's »Serse«, »Tamerlano«, »Partenope« and »Ottone«, Alessandro Stradella's »La Doriclea«, Leonardo Vinci's »Catone in Utica«, which was honoured with an ECHO Klassik award,as well as recitals with the countertenors Jakub Józef Orliński, Franco Fagioli, Max Emanuel Cencic and Xavier Sabata, with the mezzo-sopranos Ann Hallenberg and Joyce DiDonato and the sopranos Francesca Aspromonte and Emöke Barath.The recordings of Haydn's violin and harpsichord concertos as well as a cello album with Edgar Moreau were also honoured with ECHO Klassik awards in 2016. They also recorded the violin and harpsichord concertos by Johann Sebastian Bach with soloists Shunske Sato and Francesco Corti. With Dmitry Sinkovsky as soloist and conductor, Il Pomo d'Oro was honoured with the Diapason d'or for the recording of Antonio Vivaldi's violin concertos »Per Pisendel«.

Il Pomo d'Oro is an official ambassador of El Sistema Greece, a humanitarian project that offers free music lessons to children in Greek refugee camps.